Contents

  1. Correction with Known \(\mu\)
  2. Seperating Signals
  3. Empirical Coverage Proportions
  4. Possible Correction: Logit Proportions
  5. Using Reference Panel for Correction
  6. Summary of Findings
  7. Next Steps and Questions

1. Correction with Known \(\mu\)



UK10K Data

Number of simulations making up each bin:

## 
##    (0,1]    (1,2]  (2,2.5]  (2.5,3]    (3,4] (4,4.75] (4.75,6]    (6,8] 
##      262      453      264      310      665      436      665      666 
##   (8,13]  (13,16] (16,Inf] 
##      680      254      270

1000 Genomes Data

Now for the high/medium/low LD regions using 1000 genomes data: